Search results for "Innovative method"

showing 6 items of 6 documents

A novel D2O tracer method to quantify RNA turnover as a biomarker of de novo ribosomal biogenesis, in vitro, in animal models, and in human skeletal …

2017

Current methods to quantify in vivo RNA dynamics are limited. Here, we developed a novel stable isotope (D2O) methodology to quantify RNA synthesis (i.e., ribosomal biogenesis) in cells, animal models, and humans. First, proliferating C2C12 cells were incubated in D2O-enriched media and myotubes ±50 ng/ml IGF-I. Second, rat quadriceps (untrained, n = 9; 7-wk interval-“like” training, n = 13) were collected after ~3-wk D2O (70 atom %) administration, with body-water enrichment monitored via blood sampling. Finally, 10 (23 ± 1 yr) men consumed 150-ml D2O followed by 50 ml/wk and undertook 6-wk resistance exercise (6 × 8 repetitions, 75% 1-repetition maximum 3/wk) with body-water enrichment mo…

0301 basic medicinePurineMaleSalivamedicine.medical_specialtyPhysiologymuscleEndocrinology Diabetes and MetabolismRiboseBiologyribosomal biogenesisCell LineQuadriceps Muscle03 medical and health scienceschemistry.chemical_compoundMiceYoung Adult0302 clinical medicineIn vivoTandem Mass SpectrometryPhysiology (medical)Internal medicinePhysical Conditioning AnimalmedicineAnimalsHumansNucleotideDeuterium OxideRNA synthesista315D2Ochemistry.chemical_classificationSkeletal muscleRNAResistance TrainingRibosomal RNARats030104 developmental biologymedicine.anatomical_structureEndocrinologychemistryInnovative MethodologyRNAFemaleRibosomes030217 neurology & neurosurgeryBiomarkersBlood samplingAmerican Journal of Physiology: Endocrinology and Metabolism
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Digitalization ih prosthesis innovative methodology on a clinical case

2019

Digitalization prosthesis innovative methodology
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La dimensión social del lenguaje como una oportunidad educativa para la promoción del diálogo intercultural en el aula de Educación Superior

2021

[EN] For some time, it has been considered the need to approach the educational experience to the student sociocultural reality in the context of a classroom in Higher Education. This need is even more evident in the context of international exchange programs, in which the main objective is precisely to provide a space for mutual enrichment between the student's culture of origin and the host culture. In this sense, the “Grup d’Acompanyament Lingüístic” (GRUPal) works to promote the intercultural dialogue that inevitably and spontaneously takes place in and outside the classroom. The purpose of this paper is to present a didactic intervention based on inclusion and cooperative exchange as w…

Innovación educativaPolitically correct languageMetodologías innovadorasEuphemismCompetencia interculturalHigher EducationInterculturalityInterculturalidadLenguaje políticamente correctoEufemismoEducación superiorAcompañamiento lingüísticoDiversidad lingüística y culturalInnovative methodologiesIntercultural competenceEnseñanza superiorTecnologías y educaciónLinguistic and cultural diversityLinguistic supportLibro de Actas IN-RED 2021: VII Congreso de Innovación Edicativa y Docencia en Red
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Enhanced light scattering in Si nanostructures produced by pulsed laser irradiation

2013

An innovative method for Si nanostructures (NS) fabrication is proposed, through nanosecond laser irradiation (lambda = 532 nm) of thin Si film (120 nm) on quartz. Varying the laser energy fluences (425-1130 mJ/cm(2)) distinct morphologies of Si NS appear, going from interconnected structures to isolated clusters. Film breaking occurs through a laser-induced dewetting process. Raman scattering is enhanced in all the obtained Si NS, with the largest enhancement in interconnected Si structures, pointing out an increased trapping of light due to multiple scattering. The reported method is fast, scalable and cheap, and can be applied for light management in photovoltaics. (C) 2013 AIP Publishin…

Innovative methodMaterials sciencePhysics and Astronomy (miscellaneous)Settore ING-INF/01 - ElettronicaLight scatteringQuartz SiliconSettore FIS/03 - Fisica Della Materialaw.inventionsymbols.namesakeLight managementSi nanostructures NanostructurelawDewetting proceLaser energieDewettingThin filmbusiness.industryScatteringIsolated clusterLaserInterconnected structureSemiconductorsymbolsOptoelectronicsbusinessRaman spectroscopyPhotovoltaicRaman scattering
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Temporally precise control of single-neuron spiking by juxtacellular nanostimulation

2017

Temporal patterns of action potentials influence a variety of activity-dependent intra- and intercellular processes and play an important role in theories of neural coding. Elucidating the mechanisms underlying these phenomena requires imposing spike trains with precisely defined patterns, but this has been challenging due to the limitations of existing stimulation techniques. Here we present a new nanostimulation method providing control over the action potential output of individual cortical neurons. Spikes are elicited through the juxtacellular application of short-duration fluctuating currents (“kurzpulses”), allowing for the sub-millisecond precise and reproducible induction of arbitr…

Male0301 basic medicine2-amino-5-phosphopentanoic acidPatch-Clamp TechniquesTime FactorsPhysiologyComputer scienceAction Potentialsgenetics [Luminescent Proteins]pharmacology [Valine]metabolism [Cytoskeletal Proteins]Mice0302 clinical medicineCortex (anatomy)physiology [Action Potentials]genetics [Nerve Tissue Proteins]6-Cyano-7-nitroquinoxaline-23-dioneNeuronsGeneral Neurosciencepharmacology [Excitatory Amino Acid Antagonists]Valinephysiology [Neurons]medicine.anatomical_structurepharmacology [6-Cyano-7-nitroquinoxaline-23-dione]FemaleSpike (software development)Neuroinformaticsgenetics [Synapsins]Models NeurologicalBiophysicsMice TransgenicNerve Tissue ProteinsOptogenetics03 medical and health sciencesmedicinedrug effects [Neurons]Animalsmetabolism [Synapsins]ddc:610metabolism [Luminescent Proteins]activity regulated cytoskeletal-associated proteingenetics [Cytoskeletal Proteins]analogs & derivatives [Valine]metabolism [Nerve Tissue Proteins]drug effects [Action Potentials]Somatosensory CortexSynapsinsElectric StimulationOptogeneticsCytoskeletal ProteinsLuminescent Proteins030104 developmental biologynervous systemInnovative Methodologycytology [Somatosensory Cortex]NeuronWhole cellExcitatory Amino Acid AntagonistsNeuroscience030217 neurology & neurosurgeryJournal of Neurophysiology
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Zināšanu vadīšanas metožu pilnveidošana organizācijās

2013

Elektroniskā versija nesatur pielikumus

VadībzinātneZināšanu vadīšanas sistēmaBusiness managementUzņēmējdarbības vadībapersonāla attīstībaknowledge management systempersonnel developmentinovatīvās mācību metodesinnovative methods of teachingVadība un administrēšana un nekustamo īpašumu pārvaldība
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